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TAK-733 inhibits inflammatory neointimal formation by suppressing proliferation, migration, and inflammation in vitro and in vivo
As a potent and selective allosteric inhibitor of MEK, TAK-733 has been shown to exert anti-cancer effects for a wide range of cancers both in vitro and in vivo. However, its effects on inhibiting growth have never been investigated in the cardiovascular system, where regulation of abnormal vascular...
Autores principales: | Park, Jun-Hee, Kim, Sang Woo, Cha, Min-Ji, Yoon, Nara, Lee, Chang Youn, Lee, Jiyun, Seo, Hyang-Hee, Shin, Sunhye, Choi, Jung-Won, Lee, Seahyoung, Lim, Soyeon, Hwang, Ki-Chul |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5938062/ https://www.ncbi.nlm.nih.gov/pubmed/29674718 http://dx.doi.org/10.1038/s12276-018-0052-y |
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