Isolation and molecular characterization of parainfluenza virus 5 in diarrhea-affected piglets in China

Recently, parainfluenza virus 5 (PIV5) infection has been increasingly reported in mammals. In this study, five PIV5 strains were isolated from diarrhea-affected piglets from four provinces or municipalities in China. An F-gene-based phylogenetic tree indicated that the five isolated strains were cl...

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Detalles Bibliográficos
Autores principales: JIANG, Ning, WANG, Enyu, GUO, Donghua, WANG, Xin, SU, Mingjun, KONG, Fanzhi, YUAN, Dongwei, ZHAI, Junjun, SUN, Dongbo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Japanese Society of Veterinary Science 2018
Materias:
Virology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5938184/
https://www.ncbi.nlm.nih.gov/pubmed/29459504
http://dx.doi.org/10.1292/jvms.17-0581
Descripción
Sumario:Recently, parainfluenza virus 5 (PIV5) infection has been increasingly reported in mammals. In this study, five PIV5 strains were isolated from diarrhea-affected piglets from four provinces or municipalities in China. An F-gene-based phylogenetic tree indicated that the five isolated strains were closely related to the PIV5 strain ZJQ-221 from a lesser panda in China, and the PIV5 strain 1168-1 from a dog in South Korea. The new isolates differed genetically from other pig, calf, rhesus macaque kidney cells, human, and dog PIV5 reference strains. Our study reveals the presence of PIV5 in intestinal tissue samples collected from diarrhea-affected piglets, and provides novel information regarding the epidemiology and tissue tropism of PIV5.

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