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PET Imaging with S-[(11)C]Methyl-L-Cysteine and L-[Methyl-(11)C]Methionine in Rat Models of Glioma, Glioma Radiotherapy, and Neuroinflammation

PURPOSE: S-[(11)C]-methyl-L-cysteine ([(11)C]MCYS) has been claimed to offer higher tumor selectivity than L-[methyl- (11)C]methionine ([(11)C]MET). We examined this claim in animal models. PROCEDURES: Rats with implanted untreated (n = 10) or irradiated (n = 7, 1 × 25 Gy, on day 8) orthotopic gliom...

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Detalles Bibliográficos
Autores principales: Parente, Andrea, van Waarde, Aren, Shoji, Alexandre, de Paula Faria, Daniele, Maas, Bram, Zijlma, Rolf, Dierckx, Rudi A. J. O., Langendijk, Johannes A., de Vries, Erik F.J., Doorduin, Janine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5938303/
https://www.ncbi.nlm.nih.gov/pubmed/29086198
http://dx.doi.org/10.1007/s11307-017-1137-z

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