Cargando…

Compartmentalized Cyclic AMP Production by the Bordetella pertussis and Bacillus anthracis Adenylate Cyclase Toxins Differentially Affects the Immune Synapse in T Lymphocytes

A central feature of the immune synapse (IS) is the tight compartmentalization of membrane receptors and signaling mediators that is functional for its ability to coordinate T cell activation. Second messengers centrally implicated in this process, such as Ca(2+) and diacyl glycerol, also undergo co...

Descripción completa

Detalles Bibliográficos
Autores principales:	Arumugham, Vijay B., Ulivieri, Cristina, Onnis, Anna, Finetti, Francesca, Tonello, Fiorella, Ladant, Daniel, Baldari, Cosima T.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2018
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5938339/ https://www.ncbi.nlm.nih.gov/pubmed/29765373 http://dx.doi.org/10.3389/fimmu.2018.00919

Ejemplares similares

The Bordetella pertussis adenylate cyclase toxin binds to T cells via LFA-1 and induces its disengagement from the immune synapse
por: Paccani, Silvia Rossi, et al.
Publicado: (2011)

The Adenylate Cyclase Toxins of Bacillus anthracis and Bordetella pertussis Promote Th2 Cell Development by Shaping T Cell Antigen Receptor Signaling
por: Rossi Paccani, Silvia, et al.
Publicado: (2009)

Bioengineering of Bordetella pertussis Adenylate Cyclase Toxin for Antigen-Delivery and Immunotherapy
por: Chenal, Alexandre, et al.
Publicado: (2018)

Bioengineering of Bordetella pertussis Adenylate Cyclase Toxin for Vaccine Development and Other Biotechnological Purposes
por: Ladant, Daniel
Publicado: (2021)

Functional and structural consequences of epithelial cell invasion by Bordetella pertussis adenylate cyclase toxin
por: Angely, Christelle, et al.
Publicado: (2020)

The Adenylate Cyclase (CyaA) Toxin from Bordetella pertussis Has No Detectable Phospholipase A (PLA) Activity In Vitro
por: Voegele, Alexis, et al.
Publicado: (2019)

Characterization of the Intrinsic Phospholipase A1 Activity of Bordetella pertussis Adenylate Cyclase Toxin
por: González-Bullón, David, et al.
Publicado: (2018)

Stability, structural and functional properties of a monomeric, calcium–loaded adenylate cyclase toxin, CyaA, from Bordetella pertussis
por: Cannella, Sara E., et al.
Publicado: (2017)

Bordetella Adenylate Cyclase-Hemolysin Toxins
por: Guiso, Nicole
Publicado: (2017)

Interaction with adenylate cyclase toxin from Bordetella pertussis affects the metal binding properties of calmodulin
por: Springer, Tzvia I., et al.
Publicado: (2016)

Blockade of the Adenylate Cyclase Toxin Synergizes with Opsonizing Antibodies to Protect Mice against Bordetella pertussis
por: DiVenere, Andrea M., et al.
Publicado: (2022)

The Adenylate Cyclase Toxin of Bordetella pertussis Binds to Target Cells via the α(M)β(2) Integrin (Cd11b/Cd18)
por: Guermonprez, Pierre, et al.
Publicado: (2001)

Phosphoproteomics of cAMP signaling of Bordetella adenylate cyclase toxin in mouse dendritic cells
por: Novák, Jakub, et al.
Publicado: (2017)

Vesicular Trafficking to the Immune Synapse: How to Assemble Receptor-Tailored Pathways from a Basic Building Set
por: Onnis, Anna, et al.
Publicado: (2016)

Characterization of Post-Translational Modifications and Cytotoxic Properties of the Adenylate-Cyclase Hemolysin Produced by Various Bordetella pertussis and Bordetella parapertussis Isolates
por: Bouchez, Valérie, et al.
Publicado: (2017)

Site I Inactivation Impacts Calmodulin Calcium Binding and Activation of Bordetella pertussis Adenylate Cyclase Toxin
por: Johns, Christian W., et al.
Publicado: (2017)

Selective Enhancement of the Cell-Permeabilizing Activity of Adenylate Cyclase Toxin Does Not Increase Virulence of Bordetella pertussis
por: Holubova, Jana, et al.
Publicado: (2021)

Membrane Activity and Channel Formation of the Adenylate Cyclase Toxin (CyaA) of Bordetella pertussis in Lipid Bilayer Membranes
por: Knapp, Oliver, et al.
Publicado: (2020)

Orchestration of Immunological Synapse Assembly by Vesicular Trafficking
por: Onnis, Anna, et al.
Publicado: (2019)

The Eukaryotic Host Factor 14-3-3 Inactivates Adenylate Cyclase Toxins of Bordetella bronchiseptica and B. parapertussis, but Not B. pertussis
por: Fukui-Miyazaki, Aya, et al.
Publicado: (2018)

Block V RTX Domain of Adenylate Cyclase from Bordetella pertussis: A Conformationally Dynamic Scaffold for Protein Engineering Applications
por: Bulutoglu, Beyza, et al.
Publicado: (2017)

Susceptibility of primary human airway epithelial cells to Bordetella pertussis adenylate cyclase toxin in two- and three-dimensional culture conditions
por: Bianchi, Maria, et al.
Publicado: (2020)

Bordetella Adenylate Cyclase Toxin Elicits Airway Mucin Secretion through Activation of the cAMP Response Element Binding Protein
por: Malandra, Anna, et al.
Publicado: (2021)

Membrane Permeabilization by Bordetella Adenylate Cyclase Toxin Involves Pores of Tunable Size
por: González-Bullón, David, et al.
Publicado: (2019)

Structural basis for non-canonical integrin engagement by Bordetella adenylate cyclase toxin
por: Goldsmith, Jory A., et al.
Publicado: (2022)

Simultaneous Determination of Antibodies to Pertussis Toxin and Adenylate Cyclase Toxin Improves Serological Diagnosis of Pertussis
por: Knuutila, Aapo, et al.
Publicado: (2021)

Susceptibility of Human Airway Tissue Models Derived From Different Anatomical Sites to Bordetella pertussis and Its Virulence Factor Adenylate Cyclase Toxin
por: Sivarajan, Rinu, et al.
Publicado: (2021)

THE EFFECT OF BORDETELLA PERTUSSIS ON LYMPHOCYTE CYCLIC AMP METABOLISM
por: Parker, Charles W., et al.
Publicado: (1973)

Adenyl cyclases and cAMP in plant signaling - past and present
por: Gehring, Chris
Publicado: (2010)

IFT20: An Eclectic Regulator of Cellular Processes beyond Intraflagellar Transport
por: Finetti, Francesca, et al.
Publicado: (2022)

Bordetella adenylate cyclase toxin is a unique ligand of the integrin complement receptor 3
por: Osicka, Radim, et al.
Publicado: (2015)

Bordetella Pertussis Adenylate Cyclase Toxin Does Not Possess a Phospholipase A Activity; Serine 606 and Aspartate 1079 Residues Are Not Involved in Target Cell Delivery of the Adenylyl Cyclase Enzyme Domain
por: Bumba, Ladislav, et al.
Publicado: (2018)

Bordetella pertussis Commits Human Dendritic Cells to Promote a Th1/Th17 Response through the Activity of Adenylate Cyclase Toxin and MAPK-Pathways
por: Fedele, Giorgio, et al.
Publicado: (2010)

Structure–Function Relationships Underlying the Capacity of Bordetella Adenylate Cyclase Toxin to Disarm Host Phagocytes
por: Novak, Jakub, et al.
Publicado: (2017)

Transcellular communication at the immunological synapse: a vesicular traffic-mediated mutual exchange
por: Finetti, Francesca, et al.
Publicado: (2017)

A Simple Luminescent Adenylate-Cyclase Functional Assay for Evaluation of Bacillus anthracis Edema Factor Activity
por: Israeli, Ma’ayan, et al.
Publicado: (2016)

A Robust and Sensitive Spectrophotometric Assay for the Enzymatic Activity of Bacterial Adenylate Cyclase Toxins
por: Davi, Marilyne, et al.
Publicado: (2022)

Design of a Quantitative LC-MS Method for Residual Toxins Adenylate Cyclase Toxin (ACT), Dermonecrotic Toxin (DNT) and Tracheal Cytotoxin (TCT) in Bordetella pertussis Vaccines
por: Szymkowicz, Lisa, et al.
Publicado: (2021)

Regulation of Selective B Cell Autophagy by the Pro-oxidant Adaptor p66SHC
por: Onnis, Anna, et al.
Publicado: (2020)

Residues 529 to 549 participate in membrane penetration and pore-forming activity of the Bordetella adenylate cyclase toxin
por: Roderova, Jana, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_12r42tk3i779pnpltfpn5r667h