Sodium Tanshinone IIA Sulfonate Decreases Cigarette Smoke-Induced Inflammation and Oxidative Stress via Blocking the Activation of MAPK/HIF-1α Signaling Pathway

Aberrant activation of hypoxia-inducible factor (HIF)-1α is frequently encountered and promotes oxidative stress and inflammation in chronic obstructive pulmonary disease (COPD). The present study investigated whether sodium tanshinone IIA sulfonate (STS), a water-soluble derivative of tanshinone II...

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Detalles Bibliográficos
Autores principales: Guan, Ruijuan, Wang, Jian, Li, Ziying, Ding, Mingjing, Li, Defu, Xu, Guihua, Wang, Tao, Chen, Yuqin, Yang, Qian, Long, Zhen, Cai, Zhou, Zhang, Chenting, Liang, Xue, Dong, Lian, Zhao, Li, Zhang, Haiyun, Sun, Dejun, Lu, Wenju
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5938387/
https://www.ncbi.nlm.nih.gov/pubmed/29765317
http://dx.doi.org/10.3389/fphar.2018.00263

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