Design of a Type-1 Diabetes Vaccine Candidate Using Edible Plants Expressing a Major Autoantigen

Type-1 diabetes (T1D) is a metabolic disease involving the autoimmune destruction of insulin-producing pancreatic beta cells. It is often diagnosed by the detection of autoantibodies, typically those recognizing insulin itself or the 65-kDa isoform of glutamic acid decarboxylase (GAD65). Oral insuli...

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Detalles Bibliográficos
Autores principales: Bertini, Edoardo, Merlin, Matilde, Gecchele, Elisa, Puggia, Andrea, Brozzetti, Annalisa, Commisso, Mauro, Falorni, Alberto, Bini, Vittorio, Klymyuk, Victor, Pezzotti, Mario, Avesani, Linda
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Plant Science
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5938395/
https://www.ncbi.nlm.nih.gov/pubmed/29765386
http://dx.doi.org/10.3389/fpls.2018.00572

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