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Detection of DNA Double Strand Breaks by γH2AX Does Not Result in 53bp1 Recruitment in Mouse Retinal Tissues

Gene editing is an attractive potential treatment of inherited retinopathies. However, it often relies on endogenous DNA repair. Retinal DNA repair is incompletely characterized in humans and animal models. We investigated recruitment of the double stranded break (DSB) repair complex of γH2AX and 53...

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Detalles Bibliográficos
Autores principales:	Müller, Brigitte, Ellinwood, N. M., Lorenz, Birgit, Stieger, Knut
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2018
Materias:	Neuroscience
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5938408/ https://www.ncbi.nlm.nih.gov/pubmed/29765300 http://dx.doi.org/10.3389/fnins.2018.00286

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