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Overexpression of miR-202 resensitizes imatinib resistant chronic myeloid leukemia cells through targetting Hexokinase 2

Chronic myeloid leukemia (CML) is a myeloproliferative disease which uniquely expresses a constitutively active tyrosine kinase, BCR/ABL. As a specific inhibitor of the BCR-ABL tyrosine kinase, imatinib becomes the first choice for the treatment of CML due to its high efficacy and low toxicity. Howe...

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Detalles Bibliográficos
Autores principales:	Deng, Yingjun, Li, Xin, Feng, Jinxin, Zhang, Xiangliang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Portland Press Ltd. 2018
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5938424/ https://www.ncbi.nlm.nih.gov/pubmed/29559564 http://dx.doi.org/10.1042/BSR20171383

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