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Lymph Node Collision Tumor Consisting of Metastatic Pulmonary Adenocarcinoma and Diffuse Large B-cell Lymphoma

A 67-year-old man presented with a fever and general malaise. Computed tomography showed multiple nodules in the lungs and liver, associated with mediastinal and para-aortic lymphadenopathy. Bone marrow aspiration revealed diffuse large B-cell lymphoma (DLBCL). Renal and liver dysfunction and pancyt...

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Autores principales: Ikemura, Shinnosuke, Moriyama, Mitsuru, Matsumoto, Kimihiro, Nakayama, Shingo, Matsuzaki, Tatsu, Nakajima, Takahiro, Sasaki, Aya, Miyauchi, Jun, Terashima, Takeshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Japanese Society of Internal Medicine 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5938506/
https://www.ncbi.nlm.nih.gov/pubmed/29269648
http://dx.doi.org/10.2169/internalmedicine.9280-17
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author Ikemura, Shinnosuke
Moriyama, Mitsuru
Matsumoto, Kimihiro
Nakayama, Shingo
Matsuzaki, Tatsu
Nakajima, Takahiro
Sasaki, Aya
Miyauchi, Jun
Terashima, Takeshi
author_facet Ikemura, Shinnosuke
Moriyama, Mitsuru
Matsumoto, Kimihiro
Nakayama, Shingo
Matsuzaki, Tatsu
Nakajima, Takahiro
Sasaki, Aya
Miyauchi, Jun
Terashima, Takeshi
author_sort Ikemura, Shinnosuke
collection PubMed
description A 67-year-old man presented with a fever and general malaise. Computed tomography showed multiple nodules in the lungs and liver, associated with mediastinal and para-aortic lymphadenopathy. Bone marrow aspiration revealed diffuse large B-cell lymphoma (DLBCL). Renal and liver dysfunction and pancytopenia inhibited chemotherapy administration; the patient subsequently died of multiorgan failure. An autopsy revealed pulmonary adenocarcinoma with metastases to the lungs, liver, and adrenal glands; the DLBCL spread to the liver, spleen, and bone marrow. Adenocarcinoma and DLBCL collision was observed in the mediastinal and para-aortic lymph nodes. This was a rare case of collision metastasis occurring in the lymph node.
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spelling pubmed-59385062018-05-08 Lymph Node Collision Tumor Consisting of Metastatic Pulmonary Adenocarcinoma and Diffuse Large B-cell Lymphoma Ikemura, Shinnosuke Moriyama, Mitsuru Matsumoto, Kimihiro Nakayama, Shingo Matsuzaki, Tatsu Nakajima, Takahiro Sasaki, Aya Miyauchi, Jun Terashima, Takeshi Intern Med Case Report A 67-year-old man presented with a fever and general malaise. Computed tomography showed multiple nodules in the lungs and liver, associated with mediastinal and para-aortic lymphadenopathy. Bone marrow aspiration revealed diffuse large B-cell lymphoma (DLBCL). Renal and liver dysfunction and pancytopenia inhibited chemotherapy administration; the patient subsequently died of multiorgan failure. An autopsy revealed pulmonary adenocarcinoma with metastases to the lungs, liver, and adrenal glands; the DLBCL spread to the liver, spleen, and bone marrow. Adenocarcinoma and DLBCL collision was observed in the mediastinal and para-aortic lymph nodes. This was a rare case of collision metastasis occurring in the lymph node. The Japanese Society of Internal Medicine 2017-12-21 2018-04-15 /pmc/articles/PMC5938506/ /pubmed/29269648 http://dx.doi.org/10.2169/internalmedicine.9280-17 Text en Copyright © 2018 by The Japanese Society of Internal Medicine https://creativecommons.org/licenses/by-nc-nd/4.0/ The Internal Medicine is an Open Access article distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License. To view the details of this license, please visit (https://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Case Report
Ikemura, Shinnosuke
Moriyama, Mitsuru
Matsumoto, Kimihiro
Nakayama, Shingo
Matsuzaki, Tatsu
Nakajima, Takahiro
Sasaki, Aya
Miyauchi, Jun
Terashima, Takeshi
Lymph Node Collision Tumor Consisting of Metastatic Pulmonary Adenocarcinoma and Diffuse Large B-cell Lymphoma
title Lymph Node Collision Tumor Consisting of Metastatic Pulmonary Adenocarcinoma and Diffuse Large B-cell Lymphoma
title_full Lymph Node Collision Tumor Consisting of Metastatic Pulmonary Adenocarcinoma and Diffuse Large B-cell Lymphoma
title_fullStr Lymph Node Collision Tumor Consisting of Metastatic Pulmonary Adenocarcinoma and Diffuse Large B-cell Lymphoma
title_full_unstemmed Lymph Node Collision Tumor Consisting of Metastatic Pulmonary Adenocarcinoma and Diffuse Large B-cell Lymphoma
title_short Lymph Node Collision Tumor Consisting of Metastatic Pulmonary Adenocarcinoma and Diffuse Large B-cell Lymphoma
title_sort lymph node collision tumor consisting of metastatic pulmonary adenocarcinoma and diffuse large b-cell lymphoma
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5938506/
https://www.ncbi.nlm.nih.gov/pubmed/29269648
http://dx.doi.org/10.2169/internalmedicine.9280-17
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