IL-3 but not monomeric IgE regulates FcεRI levels and cell survival in primary human basophils

Binding of allergen-specific IgE to its primary receptor FcεRI on basophils and mast cells represents a central event in the development of allergic diseases. The high-affinity interaction between IgE and FcεRI results in permanent sensitization of these allergic effector cells and critically regula...

Descripción completa

Detalles Bibliográficos
Autores principales: Zellweger, Fabian, Buschor, Patrick, Hobi, Gabriel, Brigger, Daniel, Dahinden, Clemens Andreas, Villiger, Peter Matthias, Eggel, Alexander
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5938712/
https://www.ncbi.nlm.nih.gov/pubmed/29724998
http://dx.doi.org/10.1038/s41419-018-0526-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5938712/
https://www.ncbi.nlm.nih.gov/pubmed/29724998
http://dx.doi.org/10.1038/s41419-018-0526-9

Ejemplares similares