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IL-3 but not monomeric IgE regulates FcεRI levels and cell survival in primary human basophils

Binding of allergen-specific IgE to its primary receptor FcεRI on basophils and mast cells represents a central event in the development of allergic diseases. The high-affinity interaction between IgE and FcεRI results in permanent sensitization of these allergic effector cells and critically regula...

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Detalles Bibliográficos
Autores principales:	Zellweger, Fabian, Buschor, Patrick, Hobi, Gabriel, Brigger, Daniel, Dahinden, Clemens Andreas, Villiger, Peter Matthias, Eggel, Alexander
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5938712/ https://www.ncbi.nlm.nih.gov/pubmed/29724998 http://dx.doi.org/10.1038/s41419-018-0526-9

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