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Neuregulin 1 Type I Overexpression Is Associated with Reduced NMDA Receptor–Mediated Synaptic Signaling in Hippocampal Interneurons Expressing PV or CCK
Hypofunction of N-methyl-d-aspartate receptors (NMDARs) in inhibitory GABAergic interneurons is implicated in the pathophysiology of schizophrenia (SZ), a heritable disorder with many susceptibility genes. However, it is still unclear how SZ risk genes interfere with NMDAR-mediated synaptic transmis...
Autores principales: | Kotzadimitriou, Dimitrios, Nissen, Wiebke, Paizs, Melinda, Newton, Kathryn, Harrison, Paul J., Paulsen, Ole, Lamsa, Karri |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Society for Neuroscience
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5938717/ https://www.ncbi.nlm.nih.gov/pubmed/29740596 http://dx.doi.org/10.1523/ENEURO.0418-17.2018 |
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