Two Cases of Israeli Spotted Fever with Purpura Fulminans, Sharon District, Israel

We report a series of 5 case-patients who had Israeli spotted fever, of whom 2 had purpura fulminans and died. Four case-patients were given a diagnosis on the basis of PCR of skin biopsy specimens 3–4 days after treatment with doxycycline; 1 case-patient was given a diagnosis on the basis of seroco...

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Detalles Bibliográficos
Autores principales: Cohen, Regev, Babushkin, Frida, Shapiro, Maurice, Uda, Martina, Atiya-Nasagi, Yafit, Klein, Dar, Finn, Talya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Centers for Disease Control and Prevention 2018
Materias:
Synopsis
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5938761/
https://www.ncbi.nlm.nih.gov/pubmed/29664383
http://dx.doi.org/10.3201/eid2405.171992
Descripción
Sumario:We report a series of 5 case-patients who had Israeli spotted fever, of whom 2 had purpura fulminans and died. Four case-patients were given a diagnosis on the basis of PCR of skin biopsy specimens 3–4 days after treatment with doxycycline; 1 case-patient was given a diagnosis on the basis of seroconversion. Rickettsia spp. from the 2 case-patients who died were sequenced and identified as Rickettsia conorii subsp. israelensis. Purpura fulminans has been described in association with R. rickettsii and R. indica, but rarely with R. conorii subsp. israelensis.

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