Two Cases of Israeli Spotted Fever with Purpura Fulminans, Sharon District, Israel

We report a series of 5 case-patients who had Israeli spotted fever, of whom 2 had purpura fulminans and died. Four case-patients were given a diagnosis on the basis of PCR of skin biopsy specimens 3–4 days after treatment with doxycycline; 1 case-patient was given a diagnosis on the basis of seroco...

Descripción completa

Detalles Bibliográficos
Autores principales: Cohen, Regev, Babushkin, Frida, Shapiro, Maurice, Uda, Martina, Atiya-Nasagi, Yafit, Klein, Dar, Finn, Talya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Centers for Disease Control and Prevention 2018
Materias:
Synopsis
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5938761/
https://www.ncbi.nlm.nih.gov/pubmed/29664383
http://dx.doi.org/10.3201/eid2405.171992
_version_ 1783320839554334720
author Cohen, Regev
Babushkin, Frida
Shapiro, Maurice
Uda, Martina
Atiya-Nasagi, Yafit
Klein, Dar
Finn, Talya
author_facet Cohen, Regev
Babushkin, Frida
Shapiro, Maurice
Uda, Martina
Atiya-Nasagi, Yafit
Klein, Dar
Finn, Talya
author_sort Cohen, Regev
collection PubMed
description We report a series of 5 case-patients who had Israeli spotted fever, of whom 2 had purpura fulminans and died. Four case-patients were given a diagnosis on the basis of PCR of skin biopsy specimens 3–4 days after treatment with doxycycline; 1 case-patient was given a diagnosis on the basis of seroconversion. Rickettsia spp. from the 2 case-patients who died were sequenced and identified as Rickettsia conorii subsp. israelensis. Purpura fulminans has been described in association with R. rickettsii and R. indica, but rarely with R. conorii subsp. israelensis.
format Online
Article
Text
id pubmed-5938761
institution National Center for Biotechnology Information
language English
publishDate 2018
publisher Centers for Disease Control and Prevention
record_format MEDLINE/PubMed
spelling pubmed-59387612018-05-15 Two Cases of Israeli Spotted Fever with Purpura Fulminans, Sharon District, Israel Cohen, Regev Babushkin, Frida Shapiro, Maurice Uda, Martina Atiya-Nasagi, Yafit Klein, Dar Finn, Talya Emerg Infect Dis Synopsis We report a series of 5 case-patients who had Israeli spotted fever, of whom 2 had purpura fulminans and died. Four case-patients were given a diagnosis on the basis of PCR of skin biopsy specimens 3–4 days after treatment with doxycycline; 1 case-patient was given a diagnosis on the basis of seroconversion. Rickettsia spp. from the 2 case-patients who died were sequenced and identified as Rickettsia conorii subsp. israelensis. Purpura fulminans has been described in association with R. rickettsii and R. indica, but rarely with R. conorii subsp. israelensis. Centers for Disease Control and Prevention 2018-05 /pmc/articles/PMC5938761/ /pubmed/29664383 http://dx.doi.org/10.3201/eid2405.171992 Text en https://creativecommons.org/licenses/by/4.0/This is a publication of the U.S. Government. This publication is in the public domain and is therefore without copyright. All text from this work may be reprinted freely. Use of these materials should be properly cited.
spellingShingle Synopsis
Cohen, Regev
Babushkin, Frida
Shapiro, Maurice
Uda, Martina
Atiya-Nasagi, Yafit
Klein, Dar
Finn, Talya
Two Cases of Israeli Spotted Fever with Purpura Fulminans, Sharon District, Israel
title Two Cases of Israeli Spotted Fever with Purpura Fulminans, Sharon District, Israel
title_full Two Cases of Israeli Spotted Fever with Purpura Fulminans, Sharon District, Israel
title_fullStr Two Cases of Israeli Spotted Fever with Purpura Fulminans, Sharon District, Israel
title_full_unstemmed Two Cases of Israeli Spotted Fever with Purpura Fulminans, Sharon District, Israel
title_short Two Cases of Israeli Spotted Fever with Purpura Fulminans, Sharon District, Israel
title_sort two cases of israeli spotted fever with purpura fulminans, sharon district, israel
topic Synopsis
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5938761/
https://www.ncbi.nlm.nih.gov/pubmed/29664383
http://dx.doi.org/10.3201/eid2405.171992
work_keys_str_mv AT cohenregev twocasesofisraelispottedfeverwithpurpurafulminanssharondistrictisrael
AT babushkinfrida twocasesofisraelispottedfeverwithpurpurafulminanssharondistrictisrael
AT shapiromaurice twocasesofisraelispottedfeverwithpurpurafulminanssharondistrictisrael
AT udamartina twocasesofisraelispottedfeverwithpurpurafulminanssharondistrictisrael
AT atiyanasagiyafit twocasesofisraelispottedfeverwithpurpurafulminanssharondistrictisrael
AT kleindar twocasesofisraelispottedfeverwithpurpurafulminanssharondistrictisrael
AT finntalya twocasesofisraelispottedfeverwithpurpurafulminanssharondistrictisrael

Ejemplares similares