External Quality Assessment for Zika Virus Molecular Diagnostic Testing, Brazil

We conducted an external quality assessment of Zika virus molecular diagnostic tests in Brazil using a new Zika virus standard. Of 15 laboratories, 73% showed limited sensitivity and specificity. Viral load estimates varied significantly. Continuous quality assurance is required for adequate estimat...

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Detalles Bibliográficos
Autores principales: Fischer, Carlo, Pedroso, Celia, Mendrone, Alfredo, Bispo de Filippis, Ana Maria, Vallinoto, Antonio Carlos Rosário, Ribeiro, Bergmann Morais, Durigon, Edison Luiz, Marques, Ernesto T.A., Campos, Gubio S., Viana, Isabelle F.T., Levi, José Eduardo, Scarpelli, Luciano Cesar, Nogueira, Mauricio Lacerda, Bastos, Michele de Souza, Souza, Nathalia C. Santiago, Khouri, Ricardo, Lira, Sanny M. Costa, Komninakis, Shirley Vasconcelos, Baronti, Cécile, Charrel, Rémi N., Kümmerer, Beate M., Drosten, Christian, Brites, Carlos, de Lamballerie, Xavier, Niedrig, Matthias, Netto, Eduardo Martins, Drexler, Jan Felix
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Centers for Disease Control and Prevention 2018
Materias:
Dispatch
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5938781/
https://www.ncbi.nlm.nih.gov/pubmed/29470164
http://dx.doi.org/10.3201/eid2405.171747
Descripción
Sumario:We conducted an external quality assessment of Zika virus molecular diagnostic tests in Brazil using a new Zika virus standard. Of 15 laboratories, 73% showed limited sensitivity and specificity. Viral load estimates varied significantly. Continuous quality assurance is required for adequate estimates of Zika virus–associated disease and determination of patient care.

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