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Trichotillomania Ranging from “Ritual to Illness” and as a Rare Clinical Manifestation of Frontotemporal Dementia: Review of Literature and Case Report
Frontotemporal dementia (FTD) is the most common form of dementia in the younger age group and often exists with comorbid obsessions and compulsions in up to 80% of the patients. Trichotillomania or compulsive “hair-pulling” disorder is a rare manifestation of FTD and is a poorly evaluated symptom i...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Medknow Publications & Media Pvt Ltd
2018
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5939009/ https://www.ncbi.nlm.nih.gov/pubmed/29769783 http://dx.doi.org/10.4103/ijt.ijt_100_17 |
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author | Issac, Thomas Gregor Telang, Ashay Vivek Chandra, Sadanandavalli Retnaswami |
author_facet | Issac, Thomas Gregor Telang, Ashay Vivek Chandra, Sadanandavalli Retnaswami |
author_sort | Issac, Thomas Gregor |
collection | PubMed |
description | Frontotemporal dementia (FTD) is the most common form of dementia in the younger age group and often exists with comorbid obsessions and compulsions in up to 80% of the patients. Trichotillomania or compulsive “hair-pulling” disorder is a rare manifestation of FTD and is a poorly evaluated symptom in this condition. The release of “grooming functions” due to frontal disinhibition is often attributed to the evolutionary perspective; however, recent findings also implicate the role of neurotransmitter dysfunction. Trichotillomania is currently classified under obsessive and compulsive behavioral spectrum disorders and is often encountered in the younger population with research evidence of response to selective serotonin reuptake inhibitors (SSRIs), antipsychotics, and newer drugs such as N-acetyl cysteine. The role of behavioral therapy also has robust evidence in trichotillomania. We herewith report the case of a middle-aged male patient who presented with features of personality change and behavioral problems in terms of anger, agitation, and disinhibitory behavior who on detailed clinical evaluation and radiological assessment had features consistent with behavioral variant of FTD along with compulsive “hair plucking” behavior which responded minimally with SSRIs. FTD can have features of trichotillomania which is an often overlooked and relatively uncommon manifestation of dementias. Treatment options such as N-acetyl cysteine and behavioral therapy could have potential utility in this degenerative condition hitherto at an earlier stage. |
format | Online Article Text |
id | pubmed-5939009 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2018 |
publisher | Medknow Publications & Media Pvt Ltd |
record_format | MEDLINE/PubMed |
spelling | pubmed-59390092018-05-16 Trichotillomania Ranging from “Ritual to Illness” and as a Rare Clinical Manifestation of Frontotemporal Dementia: Review of Literature and Case Report Issac, Thomas Gregor Telang, Ashay Vivek Chandra, Sadanandavalli Retnaswami Int J Trichology Case Report Frontotemporal dementia (FTD) is the most common form of dementia in the younger age group and often exists with comorbid obsessions and compulsions in up to 80% of the patients. Trichotillomania or compulsive “hair-pulling” disorder is a rare manifestation of FTD and is a poorly evaluated symptom in this condition. The release of “grooming functions” due to frontal disinhibition is often attributed to the evolutionary perspective; however, recent findings also implicate the role of neurotransmitter dysfunction. Trichotillomania is currently classified under obsessive and compulsive behavioral spectrum disorders and is often encountered in the younger population with research evidence of response to selective serotonin reuptake inhibitors (SSRIs), antipsychotics, and newer drugs such as N-acetyl cysteine. The role of behavioral therapy also has robust evidence in trichotillomania. We herewith report the case of a middle-aged male patient who presented with features of personality change and behavioral problems in terms of anger, agitation, and disinhibitory behavior who on detailed clinical evaluation and radiological assessment had features consistent with behavioral variant of FTD along with compulsive “hair plucking” behavior which responded minimally with SSRIs. FTD can have features of trichotillomania which is an often overlooked and relatively uncommon manifestation of dementias. Treatment options such as N-acetyl cysteine and behavioral therapy could have potential utility in this degenerative condition hitherto at an earlier stage. Medknow Publications & Media Pvt Ltd 2018 /pmc/articles/PMC5939009/ /pubmed/29769783 http://dx.doi.org/10.4103/ijt.ijt_100_17 Text en Copyright: © 2018 International Journal of Trichology http://creativecommons.org/licenses/by-nc-sa/4.0 This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms. |
spellingShingle | Case Report Issac, Thomas Gregor Telang, Ashay Vivek Chandra, Sadanandavalli Retnaswami Trichotillomania Ranging from “Ritual to Illness” and as a Rare Clinical Manifestation of Frontotemporal Dementia: Review of Literature and Case Report |
title | Trichotillomania Ranging from “Ritual to Illness” and as a Rare Clinical Manifestation of Frontotemporal Dementia: Review of Literature and Case Report |
title_full | Trichotillomania Ranging from “Ritual to Illness” and as a Rare Clinical Manifestation of Frontotemporal Dementia: Review of Literature and Case Report |
title_fullStr | Trichotillomania Ranging from “Ritual to Illness” and as a Rare Clinical Manifestation of Frontotemporal Dementia: Review of Literature and Case Report |
title_full_unstemmed | Trichotillomania Ranging from “Ritual to Illness” and as a Rare Clinical Manifestation of Frontotemporal Dementia: Review of Literature and Case Report |
title_short | Trichotillomania Ranging from “Ritual to Illness” and as a Rare Clinical Manifestation of Frontotemporal Dementia: Review of Literature and Case Report |
title_sort | trichotillomania ranging from “ritual to illness” and as a rare clinical manifestation of frontotemporal dementia: review of literature and case report |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5939009/ https://www.ncbi.nlm.nih.gov/pubmed/29769783 http://dx.doi.org/10.4103/ijt.ijt_100_17 |
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