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Nilotinib-induced Perforating Folliculitis: Two Cases
Cutaneous adverse effects of chemotherapy are widely known but underreported. A significant advancement is made in the field of oncology with the advent of new classes of drug being added to the existing classes at a fast pace. Most of these cutaneous adverse effects are self-limiting and subsides o...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Medknow Publications & Media Pvt Ltd
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5939010/ https://www.ncbi.nlm.nih.gov/pubmed/29769784 http://dx.doi.org/10.4103/ijt.ijt_85_17 |
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author | Saraswat, Neerja Chopra, Ajay Mitra, Debdeep Talukdar, Krishna |
author_facet | Saraswat, Neerja Chopra, Ajay Mitra, Debdeep Talukdar, Krishna |
author_sort | Saraswat, Neerja |
collection | PubMed |
description | Cutaneous adverse effects of chemotherapy are widely known but underreported. A significant advancement is made in the field of oncology with the advent of new classes of drug being added to the existing classes at a fast pace. Most of these cutaneous adverse effects are self-limiting and subsides on suspending the drug either temporarily or permanently. Some of these effects are merely overlooked by the patients and the treating physician hence goes un-noticed. Nilotinib is a newer second-generation tyrosine-kinase inhibitor approved for the management of chronic myeloid leukemia. This drug is rapidly establishing itself as afirst-line therapy for chronic myeloid leukemia. Like other chemotherapeutic agents, a wide array of cutaneous adverse effects is noted with this drug. We report two cases of perforating folliculitis induced by nilotinib. |
format | Online Article Text |
id | pubmed-5939010 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2018 |
publisher | Medknow Publications & Media Pvt Ltd |
record_format | MEDLINE/PubMed |
spelling | pubmed-59390102018-05-16 Nilotinib-induced Perforating Folliculitis: Two Cases Saraswat, Neerja Chopra, Ajay Mitra, Debdeep Talukdar, Krishna Int J Trichology Case Report Cutaneous adverse effects of chemotherapy are widely known but underreported. A significant advancement is made in the field of oncology with the advent of new classes of drug being added to the existing classes at a fast pace. Most of these cutaneous adverse effects are self-limiting and subsides on suspending the drug either temporarily or permanently. Some of these effects are merely overlooked by the patients and the treating physician hence goes un-noticed. Nilotinib is a newer second-generation tyrosine-kinase inhibitor approved for the management of chronic myeloid leukemia. This drug is rapidly establishing itself as afirst-line therapy for chronic myeloid leukemia. Like other chemotherapeutic agents, a wide array of cutaneous adverse effects is noted with this drug. We report two cases of perforating folliculitis induced by nilotinib. Medknow Publications & Media Pvt Ltd 2018 /pmc/articles/PMC5939010/ /pubmed/29769784 http://dx.doi.org/10.4103/ijt.ijt_85_17 Text en Copyright: © 2018 International Journal of Trichology http://creativecommons.org/licenses/by-nc-sa/4.0 This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms. |
spellingShingle | Case Report Saraswat, Neerja Chopra, Ajay Mitra, Debdeep Talukdar, Krishna Nilotinib-induced Perforating Folliculitis: Two Cases |
title | Nilotinib-induced Perforating Folliculitis: Two Cases |
title_full | Nilotinib-induced Perforating Folliculitis: Two Cases |
title_fullStr | Nilotinib-induced Perforating Folliculitis: Two Cases |
title_full_unstemmed | Nilotinib-induced Perforating Folliculitis: Two Cases |
title_short | Nilotinib-induced Perforating Folliculitis: Two Cases |
title_sort | nilotinib-induced perforating folliculitis: two cases |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5939010/ https://www.ncbi.nlm.nih.gov/pubmed/29769784 http://dx.doi.org/10.4103/ijt.ijt_85_17 |
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