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Fenugreek, diabetes, and periodontal disease: A cross-link of sorts!

AIMS: The aim of this study was to observe the sequelae of fenugreek adjunctive to nonsurgical periodontal therapy and its comparison to a group treated with scaling and root planing (SRP) and metformin alone by assessing their respective effects on periodontal parameters, glycemic status, and serum...

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Autores principales: Sundaram, Gopalakrishnan, Ramakrishnan, Theyagarajan, Parthasarathy, Harinath, Raja, Manoj, Raj, Samuel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5939019/
https://www.ncbi.nlm.nih.gov/pubmed/29769766
http://dx.doi.org/10.4103/jisp.jisp_322_17
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author Sundaram, Gopalakrishnan
Ramakrishnan, Theyagarajan
Parthasarathy, Harinath
Raja, Manoj
Raj, Samuel
author_facet Sundaram, Gopalakrishnan
Ramakrishnan, Theyagarajan
Parthasarathy, Harinath
Raja, Manoj
Raj, Samuel
author_sort Sundaram, Gopalakrishnan
collection PubMed
description AIMS: The aim of this study was to observe the sequelae of fenugreek adjunctive to nonsurgical periodontal therapy and its comparison to a group treated with scaling and root planing (SRP) and metformin alone by assessing their respective effects on periodontal parameters, glycemic status, and serum lipid levels. MATERIALS AND METHODS: The study comprised eighty patients who were further divided into two groups. Each group consisted of 40 patients. Group 1 consisted of uncontrolled noninsulin-dependent diabetes mellitus (NIDDM) patients with chronic generalized periodontitis, who received SRP and treatment with metformin. Group 2 consisted of uncontrolled NIDDM with chronic generalized periodontitis, who received SRP and metformin plus fenugreek powder. Periodontal parameters such as gingival index, plaque index, bleeding on probing, pocket depth, and clinical attachment levels were evaluated before treatment and 1 month after nonsurgical periodontal therapy. The values of low-density lipoprotein (LDL), triglycerides, total cholesterol (TC), and glycosylated hemoglobin (HbA1c) were assessed by collecting the blood samples before treatment and 1 month after treatment. RESULTS: There was a statistically significant change in all the parameters seen clinically in both the groups. The glycemic status also showed a statistically significant reduction for fasting blood sugar (P < 0.001) on intragroup comparison. Intragroup comparison shows a statistically significant reduction (P < 0.001) for serum lipids, whereas intergroup comparison showed a statistically significant reduction after treatment only in TC and LDL levels (P < 0.02 and <0.012). CONCLUSION: This study shows that fenugreek powder can be used adjunctive to SRP to control the glycemic status and serum lipid levels in uncontrolled NIDDM patients.
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spelling pubmed-59390192018-05-16 Fenugreek, diabetes, and periodontal disease: A cross-link of sorts! Sundaram, Gopalakrishnan Ramakrishnan, Theyagarajan Parthasarathy, Harinath Raja, Manoj Raj, Samuel J Indian Soc Periodontol Original Article AIMS: The aim of this study was to observe the sequelae of fenugreek adjunctive to nonsurgical periodontal therapy and its comparison to a group treated with scaling and root planing (SRP) and metformin alone by assessing their respective effects on periodontal parameters, glycemic status, and serum lipid levels. MATERIALS AND METHODS: The study comprised eighty patients who were further divided into two groups. Each group consisted of 40 patients. Group 1 consisted of uncontrolled noninsulin-dependent diabetes mellitus (NIDDM) patients with chronic generalized periodontitis, who received SRP and treatment with metformin. Group 2 consisted of uncontrolled NIDDM with chronic generalized periodontitis, who received SRP and metformin plus fenugreek powder. Periodontal parameters such as gingival index, plaque index, bleeding on probing, pocket depth, and clinical attachment levels were evaluated before treatment and 1 month after nonsurgical periodontal therapy. The values of low-density lipoprotein (LDL), triglycerides, total cholesterol (TC), and glycosylated hemoglobin (HbA1c) were assessed by collecting the blood samples before treatment and 1 month after treatment. RESULTS: There was a statistically significant change in all the parameters seen clinically in both the groups. The glycemic status also showed a statistically significant reduction for fasting blood sugar (P < 0.001) on intragroup comparison. Intragroup comparison shows a statistically significant reduction (P < 0.001) for serum lipids, whereas intergroup comparison showed a statistically significant reduction after treatment only in TC and LDL levels (P < 0.02 and <0.012). CONCLUSION: This study shows that fenugreek powder can be used adjunctive to SRP to control the glycemic status and serum lipid levels in uncontrolled NIDDM patients. Medknow Publications & Media Pvt Ltd 2018 /pmc/articles/PMC5939019/ /pubmed/29769766 http://dx.doi.org/10.4103/jisp.jisp_322_17 Text en Copyright: © 2018 Indian Society of Periodontology http://creativecommons.org/licenses/by-nc-sa/4.0 This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms.
spellingShingle Original Article
Sundaram, Gopalakrishnan
Ramakrishnan, Theyagarajan
Parthasarathy, Harinath
Raja, Manoj
Raj, Samuel
Fenugreek, diabetes, and periodontal disease: A cross-link of sorts!
title Fenugreek, diabetes, and periodontal disease: A cross-link of sorts!
title_full Fenugreek, diabetes, and periodontal disease: A cross-link of sorts!
title_fullStr Fenugreek, diabetes, and periodontal disease: A cross-link of sorts!
title_full_unstemmed Fenugreek, diabetes, and periodontal disease: A cross-link of sorts!
title_short Fenugreek, diabetes, and periodontal disease: A cross-link of sorts!
title_sort fenugreek, diabetes, and periodontal disease: a cross-link of sorts!
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5939019/
https://www.ncbi.nlm.nih.gov/pubmed/29769766
http://dx.doi.org/10.4103/jisp.jisp_322_17
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