Oral Exposure to Paraquat Triggers Earlier Expression of Phosphorylated α-Synuclein in the Enteric Nervous System of A53T Mutant Human α-Synuclein Transgenic Mice

The misfolded α-synuclein protein, phosphorylated at serine 129 (pSer129 α-syn), is the hallmark of Parkinson disease (PD). Detected also in the enteric nervous system (ENS), it supports the recent theory that PD could start in the gut, rather than the brain. In a previous study, using a transgenic...

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Detalles Bibliográficos
Autores principales: Naudet, Nicolas, Antier, Emilie, Gaillard, Damien, Morignat, Eric, Lakhdar, Latifa, Baron, Thierry, Bencsik, Anna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5939863/
https://www.ncbi.nlm.nih.gov/pubmed/29040593
http://dx.doi.org/10.1093/jnen/nlx092

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