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LocusExplorer: a user-friendly tool for integrated visualization of human genetic association data and biological annotations

Summary: In this article, we present LocusExplorer, a data visualization and exploration tool for genetic association data. LocusExplorer is written in R using the Shiny library, providing access to powerful R-based functions through a simple user interface. LocusExplorer allows users to simultaneou...

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Detalles Bibliográficos
Autores principales: Dadaev, Tokhir, Leongamornlert, Daniel A., Saunders, Edward J., Eeles, Rosalind, Kote-Jarai, Zsofia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5939893/
https://www.ncbi.nlm.nih.gov/pubmed/26589274
http://dx.doi.org/10.1093/bioinformatics/btv690
Descripción
Sumario:Summary: In this article, we present LocusExplorer, a data visualization and exploration tool for genetic association data. LocusExplorer is written in R using the Shiny library, providing access to powerful R-based functions through a simple user interface. LocusExplorer allows users to simultaneously display genetic, statistical and biological data for humans in a single image and allows dynamic zooming and customization of the plot features. Publication quality plots may then be produced in a variety of file formats. Availability and implementation: LocusExplorer is open source and runs through R and a web browser. It is available at www.oncogenetics.icr.ac.uk/LocusExplorer/ or can be installed locally and the source code accessed from https://github.com/oncogenetics/LocusExplorer. Contact: tokhir.dadaev@icr.ac.uk