LocusExplorer: a user-friendly tool for integrated visualization of human genetic association data and biological annotations

Summary: In this article, we present LocusExplorer, a data visualization and exploration tool for genetic association data. LocusExplorer is written in R using the Shiny library, providing access to powerful R-based functions through a simple user interface. LocusExplorer allows users to simultaneou...

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Detalles Bibliográficos
Autores principales: Dadaev, Tokhir, Leongamornlert, Daniel A., Saunders, Edward J., Eeles, Rosalind, Kote-Jarai, Zsofia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Applications Notes
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5939893/
https://www.ncbi.nlm.nih.gov/pubmed/26589274
http://dx.doi.org/10.1093/bioinformatics/btv690
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author Dadaev, Tokhir
Leongamornlert, Daniel A.
Saunders, Edward J.
Eeles, Rosalind
Kote-Jarai, Zsofia
author_facet Dadaev, Tokhir
Leongamornlert, Daniel A.
Saunders, Edward J.
Eeles, Rosalind
Kote-Jarai, Zsofia
author_sort Dadaev, Tokhir
collection PubMed
description Summary: In this article, we present LocusExplorer, a data visualization and exploration tool for genetic association data. LocusExplorer is written in R using the Shiny library, providing access to powerful R-based functions through a simple user interface. LocusExplorer allows users to simultaneously display genetic, statistical and biological data for humans in a single image and allows dynamic zooming and customization of the plot features. Publication quality plots may then be produced in a variety of file formats. Availability and implementation: LocusExplorer is open source and runs through R and a web browser. It is available at www.oncogenetics.icr.ac.uk/LocusExplorer/ or can be installed locally and the source code accessed from https://github.com/oncogenetics/LocusExplorer. Contact: tokhir.dadaev@icr.ac.uk
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spelling pubmed-59398932018-08-07 LocusExplorer: a user-friendly tool for integrated visualization of human genetic association data and biological annotations Dadaev, Tokhir Leongamornlert, Daniel A. Saunders, Edward J. Eeles, Rosalind Kote-Jarai, Zsofia Bioinformatics Applications Notes Summary: In this article, we present LocusExplorer, a data visualization and exploration tool for genetic association data. LocusExplorer is written in R using the Shiny library, providing access to powerful R-based functions through a simple user interface. LocusExplorer allows users to simultaneously display genetic, statistical and biological data for humans in a single image and allows dynamic zooming and customization of the plot features. Publication quality plots may then be produced in a variety of file formats. Availability and implementation: LocusExplorer is open source and runs through R and a web browser. It is available at www.oncogenetics.icr.ac.uk/LocusExplorer/ or can be installed locally and the source code accessed from https://github.com/oncogenetics/LocusExplorer. Contact: tokhir.dadaev@icr.ac.uk Oxford University Press 2016-03-15 2015-11-20 /pmc/articles/PMC5939893/ /pubmed/26589274 http://dx.doi.org/10.1093/bioinformatics/btv690 Text en © The Author 2015. Published by Oxford University Press. http://creativecommons.org/licenses/by/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Applications Notes
Dadaev, Tokhir
Leongamornlert, Daniel A.
Saunders, Edward J.
Eeles, Rosalind
Kote-Jarai, Zsofia
LocusExplorer: a user-friendly tool for integrated visualization of human genetic association data and biological annotations
title LocusExplorer: a user-friendly tool for integrated visualization of human genetic association data and biological annotations
title_full LocusExplorer: a user-friendly tool for integrated visualization of human genetic association data and biological annotations
title_fullStr LocusExplorer: a user-friendly tool for integrated visualization of human genetic association data and biological annotations
title_full_unstemmed LocusExplorer: a user-friendly tool for integrated visualization of human genetic association data and biological annotations
title_short LocusExplorer: a user-friendly tool for integrated visualization of human genetic association data and biological annotations
title_sort locusexplorer: a user-friendly tool for integrated visualization of human genetic association data and biological annotations
topic Applications Notes
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5939893/
https://www.ncbi.nlm.nih.gov/pubmed/26589274
http://dx.doi.org/10.1093/bioinformatics/btv690
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