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Tiotropium inhibits methacholine-induced extracellular matrix production via β-catenin signaling in human airway smooth muscle cells

BACKGROUND: Airway remodeling is an important feature of chronic obstructive pulmonary disease (COPD) that is associated with disease severity and irreversible airflow limitation. An extensive alteration of the extracellular matrix (ECM) surrounding the airway smooth muscle (ASM) bundle is one of th...

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Detalles Bibliográficos
Autores principales:	Huo, Yating, Guan, Lili, Xu, Jiawen, Zhou, Luqian, Chen, Rongchang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove Medical Press 2018
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5939907/ https://www.ncbi.nlm.nih.gov/pubmed/29765214 http://dx.doi.org/10.2147/COPD.S158552

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