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Analyzing synergistic and non-synergistic interactions in signalling pathways using Boolean Nested Effect Models

Motivation: Understanding the structure and interplay of cellular signalling pathways is one of the great challenges in molecular biology. Boolean Networks can infer signalling networks from observations of protein activation. In situations where it is difficult to assess protein activation directly...

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Detalles Bibliográficos
Autores principales: Pirkl, Martin, Hand, Elisabeth, Kube, Dieter, Spang, Rainer
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5939970/
https://www.ncbi.nlm.nih.gov/pubmed/26581413
http://dx.doi.org/10.1093/bioinformatics/btv680