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Analyzing synergistic and non-synergistic interactions in signalling pathways using Boolean Nested Effect Models
Motivation: Understanding the structure and interplay of cellular signalling pathways is one of the great challenges in molecular biology. Boolean Networks can infer signalling networks from observations of protein activation. In situations where it is difficult to assess protein activation directly...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5939970/ https://www.ncbi.nlm.nih.gov/pubmed/26581413 http://dx.doi.org/10.1093/bioinformatics/btv680 |