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Oxidative stress-mediated senescence in mesenchymal progenitor cells causes the loss of their fibro/adipogenic potential and abrogates myoblast fusion
Sarcopenia is the age-related loss of skeletal muscle mass and function. Skeletal muscle comprises diverse progenitor cells, including mesenchymal progenitor cells (MPCs), which normally support myogenic cell function but cause a decline in skeletal muscle function after differentiating into fibrous...
Autores principales: | Sugihara, Hidetoshi, Teramoto, Naomi, Yamanouchi, Keitaro, Matsuwaki, Takashi, Nishihara, Masugi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5940129/ https://www.ncbi.nlm.nih.gov/pubmed/29695641 http://dx.doi.org/10.18632/aging.101425 |
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