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Oxidative stress-mediated senescence in mesenchymal progenitor cells causes the loss of their fibro/adipogenic potential and abrogates myoblast fusion

Sarcopenia is the age-related loss of skeletal muscle mass and function. Skeletal muscle comprises diverse progenitor cells, including mesenchymal progenitor cells (MPCs), which normally support myogenic cell function but cause a decline in skeletal muscle function after differentiating into fibrous...

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Detalles Bibliográficos
Autores principales: Sugihara, Hidetoshi, Teramoto, Naomi, Yamanouchi, Keitaro, Matsuwaki, Takashi, Nishihara, Masugi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5940129/
https://www.ncbi.nlm.nih.gov/pubmed/29695641
http://dx.doi.org/10.18632/aging.101425

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