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The Molecular Chaperone HSP90 Promotes Notch Signaling in the Germline of Caenorhabditis elegans

In a genetic screen to identify genes that promote GLP-1/Notch signaling in Caenorhabditis elegans germline stem cells, we found a single mutation, om40, defining a gene called ego-3. ego-3(om40) causes several defects in the soma and the germline, including paralysis during larval development, ster...

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Detalles Bibliográficos
Autores principales: Lissemore, James L., Connors, Elyse, Liu, Ying, Qiao, Li, Yang, Bing, Edgley, Mark L., Flibotte, Stephane, Taylor, Jon, Au, Vinci, Moerman, Donald G., Maine, Eleanor M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Genetics Society of America 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5940146/
https://www.ncbi.nlm.nih.gov/pubmed/29507057
http://dx.doi.org/10.1534/g3.118.300551