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Programmable Single and Multiplex Base-Editing in Bombyx mori Using RNA-Guided Cytidine Deaminases

Genome editing using standard tools (ZFN, TALEN, and CRISPR/Cas9) rely on double strand breaks to edit the genome. A series of new CRISPR tools that convert cytidine to thymine (C to T) without the requirement for DNA double-strand breaks was developed recently and quickly applied in a variety of or...

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Detalles Bibliográficos
Autores principales:	Li, Yufeng, Ma, Sanyuan, Sun, Le, Zhang, Tong, Chang, Jiasong, Lu, Wei, Chen, Xiaoxu, Liu, Yue, Wang, Xiaogang, Shi, Run, Zhao, Ping, Xia, Qingyou
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Genetics Society of America 2018
Materias:	Investigation
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5940161/ https://www.ncbi.nlm.nih.gov/pubmed/29555822 http://dx.doi.org/10.1534/g3.118.200134

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