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Predicting potential drug-drug interactions on topological and semantic similarity features using statistical learning

Drug-drug interaction (DDI) is a change in the effect of a drug when patient takes another drug. Characterizing DDIs is extremely important to avoid potential adverse drug reactions. We represent DDIs as a complex network in which nodes refer to drugs and links refer to their potential interactions....

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Detalles Bibliográficos
Autores principales: Kastrin, Andrej, Ferk, Polonca, Leskošek, Brane
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5940181/
https://www.ncbi.nlm.nih.gov/pubmed/29738537
http://dx.doi.org/10.1371/journal.pone.0196865