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Defensive effect of microRNA-200b/c against amyloid-beta peptide-induced toxicity in Alzheimer's disease models

MiRNA molecules are important post-transcriptional regulators of gene expression in the brain function. Altered miRNA profiles could represent a defensive response against the pathogenesis of neurodegenerative disorders, such as Alzheimer's disease (AD). Endogenous miRNAs have lower toxic effec...

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Detalles Bibliográficos
Autores principales: Higaki, Sayuri, Muramatsu, Masashi, Matsuda, Akio, Matsumoto, Kenji, Satoh, Jun-ichi, Michikawa, Makoto, Niida, Shumpei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5940223/
https://www.ncbi.nlm.nih.gov/pubmed/29738527
http://dx.doi.org/10.1371/journal.pone.0196929