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Defensive effect of microRNA-200b/c against amyloid-beta peptide-induced toxicity in Alzheimer's disease models
MiRNA molecules are important post-transcriptional regulators of gene expression in the brain function. Altered miRNA profiles could represent a defensive response against the pathogenesis of neurodegenerative disorders, such as Alzheimer's disease (AD). Endogenous miRNAs have lower toxic effec...
Autores principales: | Higaki, Sayuri, Muramatsu, Masashi, Matsuda, Akio, Matsumoto, Kenji, Satoh, Jun-ichi, Michikawa, Makoto, Niida, Shumpei |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5940223/ https://www.ncbi.nlm.nih.gov/pubmed/29738527 http://dx.doi.org/10.1371/journal.pone.0196929 |
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