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Ciliary margin-derived BMP4 does not have a major role in ocular development

Heterozygous Bmp4 mutations in humans and mice cause severe ocular anterior segment dysgenesis (ASD). Abnormalities include pupil displacement, corneal opacity, iridocorneal adhesions, and variable intraocular pressure, as well as some retinal and vascular defects. It is presently not known what sou...

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Detalles Bibliográficos
Autores principales: Rausch, Rebecca L., Libby, Richard T., Kiernan, Amy E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5940228/
https://www.ncbi.nlm.nih.gov/pubmed/29738572
http://dx.doi.org/10.1371/journal.pone.0197048

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