Statins impact primary embryonic mouse neural stem cell survival, cell death, and fate through distinct mechanisms

Statins inhibit HMG-CoA reductase, the rate-limiting enzyme in the cholesterol biosynthesis pathway (CBP), and are used for the prevention of cardiovascular disease. The anti-inflammatory effects of statins may also provide therapeutic benefits and have led to their use in clinical trials for preecl...

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Detalles Bibliográficos
Autores principales: Carson, Ross A., Rudine, Anthony C., Tally, Serena J., Franks, Alexis L., Frahm, Krystle A., Waldman, Jacob K., Silswal, Neerupma, Burale, Suban, Phan, James V., Chandran, Uma R., Monaghan, A. Paula, DeFranco, Donald B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5940229/
https://www.ncbi.nlm.nih.gov/pubmed/29738536
http://dx.doi.org/10.1371/journal.pone.0196387

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5940229/
https://www.ncbi.nlm.nih.gov/pubmed/29738536
http://dx.doi.org/10.1371/journal.pone.0196387

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