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Mechanical unfolding reveals stable 3-helix intermediates in talin and α-catenin
Mechanical stability is a key feature in the regulation of structural scaffolding proteins and their functions. Despite the abundance of α-helical structures among the human proteome and their undisputed importance in health and disease, the fundamental principles of their behavior under mechanical...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5940241/ https://www.ncbi.nlm.nih.gov/pubmed/29698481 http://dx.doi.org/10.1371/journal.pcbi.1006126 |