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Dimerization of the voltage-sensing phosphatase controls its voltage-sensing and catalytic activity
Multimerization is a key characteristic of most voltage-sensing proteins. The main exception was thought to be the Ciona intestinalis voltage-sensing phosphatase (Ci-VSP). In this study, we show that multimerization is also critical for Ci-VSP function. Using coimmunoprecipitation and single-molecul...
Autores principales: | Rayaprolu, Vamseedhar, Royal, Perrine, Stengel, Karen, Sandoz, Guillaume, Kohout, Susy C. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Rockefeller University Press
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5940254/ https://www.ncbi.nlm.nih.gov/pubmed/29695412 http://dx.doi.org/10.1085/jgp.201812064 |
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