Termination of T cell priming relies on a phase of unresponsiveness promoting disengagement from APCs and T cell division

T cells are primed in secondary lymphoid organs by establishing stable interactions with antigen-presenting cells (APCs). However, the cellular mechanisms underlying the termination of T cell priming and the initiation of clonal expansion remain largely unknown. Using intravital imaging, we observed...

Descripción completa

Detalles Bibliográficos
Autores principales: Bohineust, Armelle, Garcia, Zacarias, Beuneu, Hélène, Lemaître, Fabrice, Bousso, Philippe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2018
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5940264/
https://www.ncbi.nlm.nih.gov/pubmed/29588347
http://dx.doi.org/10.1084/jem.20171708

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5940264/
https://www.ncbi.nlm.nih.gov/pubmed/29588347
http://dx.doi.org/10.1084/jem.20171708

Ejemplares similares