Cargando…
Altered compensatory cytokine signaling underlies the discrepancy between Flt3(–/–) and Flt3l(–/–) mice
The receptor Flt3 and its ligand Flt3L are both critical for dendritic cell (DC) development, but DC deficiency is more severe in Flt3l(−/−) mice than in Flt3(−/−) mice. This has led to speculation that Flt3L binds to another receptor that also supports DC development. However, we found that Flt3L a...
| Autores principales: | , , , , , , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Rockefeller University Press
2018
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5940266/ https://www.ncbi.nlm.nih.gov/pubmed/29572360 http://dx.doi.org/10.1084/jem.20171784 |