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Repressing the repressor: Ezh2 mediates macrophage activation

In this issue of JEM, Zhang et al. (https://doi.org/10.1084/jem.20171417) show that the suppressive epigenetic enzyme Ezh2 is an important regulator of macrophage activation. The absence of Ezh2 leads to reduced cytokine secretion and suppresses macrophage-dependent disease development. They identif...

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Detalles Bibliográficos
Autores principales:	Neele, Annette E., de Winther, Menno P.J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Rockefeller University Press 2018
Materias:	News
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5940273/ https://www.ncbi.nlm.nih.gov/pubmed/29691302 http://dx.doi.org/10.1084/jem.20180479

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