Primary cilia sensitize endothelial cells to BMP and prevent excessive vascular regression

Blood flow shapes vascular networks by orchestrating endothelial cell behavior and function. How endothelial cells read and interpret flow-derived signals is poorly understood. Here, we show that endothelial cells in the developing mouse retina form and use luminal primary cilia to stabilize vessel...

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Detalles Bibliográficos
Autores principales: Vion, Anne-Clémence, Alt, Silvanus, Klaus-Bergmann, Alexandra, Szymborska, Anna, Zheng, Tuyu, Perovic, Tijana, Hammoutene, Adel, Oliveira, Marta Bastos, Bartels-Klein, Eireen, Hollfinger, Irene, Rautou, Pierre-Emmanuel, Bernabeu, Miguel O., Gerhardt, Holger
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2018
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5940299/
https://www.ncbi.nlm.nih.gov/pubmed/29500191
http://dx.doi.org/10.1083/jcb.201706151

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