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PI(4,5)P(2) controls plasma membrane PI4P and PS levels via ORP5/8 recruitment to ER–PM contact sites
Phosphatidylinositol 4,5-bisphosphate (PI(4,5)P(2)) is a critically important regulatory lipid of the plasma membrane (PM); however, little is known about how cells regulate PM PI(4,5)P(2) levels. Here, we show that the phosphatidylinositol 4-phosphate (PI4P)/phosphatidylserine (PS) transfer activit...
Autores principales: | Sohn, Mira, Korzeniowski, Marek, Zewe, James P., Wills, Rachel C., Hammond, Gerald R.V., Humpolickova, Jana, Vrzal, Lukas, Chalupska, Dominika, Veverka, Vaclav, Fairn, Gregory D., Boura, Evzen, Balla, Tamas |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Rockefeller University Press
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5940310/ https://www.ncbi.nlm.nih.gov/pubmed/29472386 http://dx.doi.org/10.1083/jcb.201710095 |
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