Cancer cell-selective, clathrin-mediated endocytosis of aptamer decorated nanoparticles

Lung cancer is the leading cause of cancer mortality worldwide, resulting in 88% deaths of all diagnosed patients. Hence, novel therapeutic modalities are urgently needed. Single-stranded oligonucleotide-based aptamers (APTs) are excellent ligands for tumor cell targeting. However, the molecular mec...

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Detalles Bibliográficos
Autores principales: Engelberg, Shira, Modrejewski, Julia, Walter, Johanna G., Livney, Yoav D., Assaraf, Yehuda G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2018
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5940367/
https://www.ncbi.nlm.nih.gov/pubmed/29765515
http://dx.doi.org/10.18632/oncotarget.24772

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5940367/
https://www.ncbi.nlm.nih.gov/pubmed/29765515
http://dx.doi.org/10.18632/oncotarget.24772

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