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Cancer cell-selective, clathrin-mediated endocytosis of aptamer decorated nanoparticles
Lung cancer is the leading cause of cancer mortality worldwide, resulting in 88% deaths of all diagnosed patients. Hence, novel therapeutic modalities are urgently needed. Single-stranded oligonucleotide-based aptamers (APTs) are excellent ligands for tumor cell targeting. However, the molecular mec...
Autores principales: | Engelberg, Shira, Modrejewski, Julia, Walter, Johanna G., Livney, Yoav D., Assaraf, Yehuda G. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5940367/ https://www.ncbi.nlm.nih.gov/pubmed/29765515 http://dx.doi.org/10.18632/oncotarget.24772 |
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