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20(S)-protopanaxadiol regio-selectively targets androgen receptor: anticancer effects in castration-resistant prostate tumors

We have explored the effects of 20(S)-protopanaxadiol (aPPD), a naturally derived ginsenoside, against androgen receptor (AR) positive castration resistant prostate cancer (CRPC) xenograft tumors and have examined its interactions with AR. In silico docking studies for aPPD binding to AR, alongside...

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Detalles Bibliográficos
Autores principales:	Ben-Eltriki, Mohamed, Deb, Subrata, Hassona, Mohamed, Meckling, Gray, Fazli, Ladan, Chin, Mei Yieng, Lallous, Nada, Yamazaki, Takeshi, Jia, William, Rennie, Paul S., Cherkasov, Artem, Tomlinson Guns, Emma S.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2018
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5940378/ https://www.ncbi.nlm.nih.gov/pubmed/29765513 http://dx.doi.org/10.18632/oncotarget.24695

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