Targeting the mevalonate pathway is a novel therapeutic approach to inhibit oncogenic FoxM1 transcription factor in human hepatocellular carcinoma

Dysregulation of cell metabolism is a hallmark of cancer. The mevalonate pathway in lipid metabolism has been implicated as a potential target of cancer therapy for hepatocellular carcinoma (HCC). The role of the Forkhead Box M1 (FoxM1) transcription factor in HCC development has been well documente...

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Detalles Bibliográficos
Autores principales: Ogura, Satoshi, Yoshida, Yuichi, Kurahashi, Tomohide, Egawa, Mayumi, Furuta, Kunimaro, Kiso, Shinichi, Kamada, Yoshihiro, Hikita, Hayato, Eguchi, Hidetoshi, Ogita, Hisakazu, Doki, Yuichiro, Mori, Masaki, Tatsumi, Tomohide, Takehara, Tetsuo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2018
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5940385/
https://www.ncbi.nlm.nih.gov/pubmed/29765517
http://dx.doi.org/10.18632/oncotarget.24781

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5940385/
https://www.ncbi.nlm.nih.gov/pubmed/29765517
http://dx.doi.org/10.18632/oncotarget.24781

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