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BI2536 induces mitotic catastrophe and radiosensitization in human oral cancer cells

BI2536 has been developed as a potential therapeutic agent for various cancers but not in oral cancer cells. Since BI2536 exhibits mitosis-regulating activity which are the most radiosensitive, we hypothesized that BI2536 might modulate the radiosensitivity of oral cancer cells. Human normal fibrobl...

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Detalles Bibliográficos
Autores principales: Cheng, Chieh-Yuan, Liu, Chung-Ji, Huang, Yu-Chuen, Wu, Shu-Hua, Fang, Hsu-Wei, Chen, Yu-Jen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5940398/
https://www.ncbi.nlm.nih.gov/pubmed/29765534
http://dx.doi.org/10.18632/oncotarget.25035

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