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Assessing causal estimates of the association of obesity-related traits with coronary artery disease using a Mendelian randomization approach

Obesity-related traits have been associated with coronary artery disease (CAD) in observational studies, but these associations may be biased by confounding factors and reverse causation. In this study, we specifically conducted two-sample Mendelian randomization (MR) analyses to overcome these limi...

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Detalles Bibliográficos
Autores principales: Zhang, Xue, Lv, Wan-Qiang, Qiu, Bo, Zhang, Li-Jun, Qin, Jian, Tang, Feng-Juan, Wang, Hai-Tao, Li, Hua-Jie, Hao, Ya-Rong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5940685/
https://www.ncbi.nlm.nih.gov/pubmed/29739994
http://dx.doi.org/10.1038/s41598-018-25305-y