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Mucosal Immunity and Protective Efficacy of Intranasal Inactivated Influenza Vaccine Is Improved by Chitosan Nanoparticle Delivery in Pigs
Annually, swine influenza A virus (SwIAV) causes severe economic loss to swine industry. Currently used inactivated SwIAV vaccines administered by intramuscular injection provide homologous protection, but limited heterologous protection against constantly evolving field viruses, attributable to the...
Autores principales: | Dhakal, Santosh, Renu, Sankar, Ghimire, Shristi, Shaan Lakshmanappa, Yashavanth, Hogshead, Bradley T., Feliciano-Ruiz, Ninoshkaly, Lu, Fangjia, HogenEsch, Harm, Krakowka, Steven, Lee, Chang Won, Renukaradhya, Gourapura J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5940749/ https://www.ncbi.nlm.nih.gov/pubmed/29770135 http://dx.doi.org/10.3389/fimmu.2018.00934 |
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