Bile acids and their respective conjugates elicit different responses in neonatal cardiomyocytes: role of Gi protein, muscarinic receptors and TGR5

Bile acids are recognised as bioactive signalling molecules. While they are known to influence arrhythmia susceptibility in cholestasis, there is limited knowledge about the underlying mechanisms. To delineate mechanisms underlying fetal heart rhythm disturbances in cholestatic pregnancy, we used FR...

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Detalles Bibliográficos
Autores principales: Ibrahim, Effendi, Diakonov, Ivan, Arunthavarajah, Dulasi, Swift, Teresa, Goodwin, Mary, McIlvride, Saraid, Nikolova, Vanya, Williamson, Catherine, Gorelik, Julia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5940781/
https://www.ncbi.nlm.nih.gov/pubmed/29740092
http://dx.doi.org/10.1038/s41598-018-25569-4

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