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Acute Physiology and Neurologic Outcomes after Brain Injury in SCOP/PHLPP1 KO Mice

Suprachiasmatic nucleus circadian oscillatory protein (SCOP) (a.k.a. PHLPP1) regulates long-term memory consolidation in the brain. Using a mouse model of controlled cortical impact (CCI) we tested if (1) brain tissue levels of SCOP/PHLPP1 increase after a traumatic brain injury (TBI), and (2) if SC...

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Detalles Bibliográficos
Autores principales: Jackson, Travis C., Dixon, C. Edward, Janesko-Feldman, Keri, Vagni, Vincent, Kotermanski, Shawn E., Jackson, Edwin K., Kochanek, Patrick M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5940799/
https://www.ncbi.nlm.nih.gov/pubmed/29739983
http://dx.doi.org/10.1038/s41598-018-25371-2