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The effect of high fat diet and metformin treatment on liver lipids accumulation and their impact on insulin action

We sought to determine whether metformin treatment reverses a high-fat diet (HFD)-induced hepatic insulin resistance (IRes) and to identify lipid intermediates involved in induction of liver IRes. The experiments were conducted on male Wistar rats divided into three groups: 1. Control, 2. fed HFD an...

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Detalles Bibliográficos
Autores principales: Zabielski, Piotr, Hady, Hady Razak, Chacinska, Marta, Roszczyc, Kamila, Gorski, Jan, Blachnio-Zabielska, Agnieszka U.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5940807/
https://www.ncbi.nlm.nih.gov/pubmed/29739997
http://dx.doi.org/10.1038/s41598-018-25397-6