Heparin inhibits intracellular Mycobacterium tuberculosis bacterial replication by reducing iron levels in human macrophages

Iron is a crucial micronutrient for both mammals and their associated pathogens, and extensive literature has shown that Mycobacterium tuberculosis (Mtb) bacilli inhibited from acquiring iron from the host are severely attenuated. In contrast, increased dietary iron concentrations or patients with h...

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Detalles Bibliográficos
Autores principales: Abreu, Rodrigo, Essler, Lauren, Loy, Allyson, Quinn, Frederick, Giri, Pramod
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5940867/
https://www.ncbi.nlm.nih.gov/pubmed/29740038
http://dx.doi.org/10.1038/s41598-018-25480-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5940867/
https://www.ncbi.nlm.nih.gov/pubmed/29740038
http://dx.doi.org/10.1038/s41598-018-25480-y

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